Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950621 | 1.00 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL9627370 | 1.00 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL8376762 | 0.89 | GPR84 (0.46) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL465398 | 0.86 | GPR84 (0.43) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL27914015 | 0.83 | SPHK1 (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL3934071 | 0.81 | SPHK1 (0.45) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL9949685 | 0.80 | SPHK1 (0.43) | SPHK1GPR84FFAR1LMNATP53 | |
| SCHEMBL3925045 | 0.79 | GPR84 (0.46) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL758208 | 0.79 | GPR84 (0.46) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL753596 | 0.79 | GPR84 (0.46) | SPHK1GPR84FFAR1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068089-B2 | PROCESS FOR THE PREPARATION OF QUATERNARY AMMONIUM COMPOUNDS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-04-15 | — | — | EP | disclosed |
| US-4492802-A | QUATERNIZATION OF TERTIARY AMINE WITH EPOXY COMPOUND | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1985-01-08 | — | — | US | disclosed |
| US-4480126-A | Process for the preparation of quaternary ammonium compounds | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4421932-A | Manufacture of quaternary ammonium compounds | HENKEL KGAA (DE) | 1983-12-20 | — | — | US | disclosed |