Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931080 | 0.87 | FAAH (0.75) | FAAHMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3941135 | 0.86 | FAAH (1.00) | FAAHMAPK1ALDH1A1 | |
| SCHEMBL3933627 | 0.86 | FAAH (0.73) | FAAHTSHRMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3931485 | 0.86 | FAAH (0.73) | FAAHTSHRMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3937438 | 0.86 | FAAH (0.73) | FAAHTSHRMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3932389 | 0.85 | FAAH (0.72) | FAAHMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3934554 | 0.85 | FAAH (0.72) | FAAHTSHRMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3931338 | 0.85 | FAAH (0.79) | FAAHMAPK1MKNK1ALDH1A1 | |
| SCHEMBL3934758 | 0.85 | FAAH (0.80) | FAAHMAPK1ALDH1A1 | |
| SCHEMBL3942978 | 0.85 | FAAH (0.86) | FAAHTSHRMAPK1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |