Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942906 | 0.88 | SSTR4 (0.44) | ALDH1A1GAASSTR4HDAC3HDAC1 | |
| SCHEMBL25516873 | 0.80 | SSTR4 (0.46) | SSTR4KMT2AMAPTHPGDLMNA | |
| SCHEMBL30174862 | 0.80 | SSTR4 (0.46) | SSTR4KMT2AMAPTHPGDLMNA | |
| SCHEMBL7852494 | 0.80 | SSTR4 (0.52) | ALDH1A1SSTR4EGFRTSHRHPGD | |
| SCHEMBL30174644 | 0.79 | SSTR4 (0.50) | SSTR4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL25516985 | 0.79 | SSTR4 (0.50) | SSTR4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1801696 | 0.78 | HDAC1 (0.42) | ALDH1A1GAAGFERTLR7HDAC3 | |
| SCHEMBL27767983 | 0.78 | SSTR4 (0.43) | ALDH1A1GAASSTR4KMT2AHPGD | |
| SCHEMBL13849611 | 0.77 | TLR7 (0.42) | SSTR4CYP4F2CYP4A11TLR7HDAC3 | |
| SCHEMBL1800461 | 0.75 | PTGDR2 (0.46) | ALDH1A1MTNR1AMTNR1BKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |