Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935303 | 0.81 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL3937893 | 0.77 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL3930559 | 0.70 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL3929629 | 0.69 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL3935342 | 0.68 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL1378398 | 0.67 | ESR2 (1.00) | ESR1ESR2 | |
| SCHEMBL16616411 | 0.66 | ALDH1A1 (0.44) | ESR1ESR2 | |
| SCHEMBL13958288 | 0.66 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL3921680 | 0.65 | ESR1 (0.65) | ESR1ESR2 | |
| SCHEMBL27638492 | 0.64 | ESR2 (0.43) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009417-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF PREVENTING, TREATING, OR INHIBITING INFLAMMATORY DISEASES, DISORDERS, OR CONDITIONS OF THE SKIN, AND DISEASES, DISORDERS, OR CONDITIONS ASSOCIATED WITH COLLAGEN DEPLETION | WYETH (US) | 2009-01-15 | — | — | WO | disclosed |