Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939171 | 0.91 | FAAH (0.77) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3943921 | 0.90 | FAAH (0.75) | FAAHALDH1A1GRM4 | |
| SCHEMBL3943262 | 0.89 | FAAH (0.76) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3936957 | 0.88 | FAAH (0.75) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3938565 | 0.88 | FAAH (0.77) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3934364 | 0.88 | FAAH (0.77) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3936894 | 0.88 | FAAH (0.79) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3931443 | 0.88 | FAAH (0.77) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3942409 | 0.88 | FAAH (0.77) | FAAHALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3942824 | 0.87 | FAAH (0.71) | FAAHALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |