Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.46 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16031895 | 0.86 | MAOB (0.55) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL6467512 | 0.81 | MAOB (0.53) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL873385 | 0.79 | MAOB (0.51) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL22491482 | 0.78 | MAOB (0.50) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL4653072 | 0.77 | MAOB (0.53) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL2794321 | 0.76 | MAOB (0.51) | MAOBRAB9AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL18587804 | 0.73 | MAOB (0.49) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL943678 | 0.73 | MAOB (0.56) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL30788655 | 0.73 | MAOB (0.56) | MAOBRAB9AHTTL3MBTL1SOD1 | |
| SCHEMBL873981 | 0.72 | MAOB (0.51) | MAOBRAB9AHTTL3MBTL1SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005460-A1 | SMALL MOLECULE INHIBITORS OF NAVL.7 SODIUM CHANNELS FOR THE TREATMENT OF PAIN DISORDERS | ASTRAZENECA AB (SE) | 2009-01-08 | — | — | WO | disclosed |