Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.51 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873981 | 0.82 | MAOB (0.51) | MAOBSOD1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3934890 | 0.79 | MAOB (0.49) | MAOBSOD1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL16031895 | 0.78 | MAOB (0.55) | MAOBSOD1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2496417 | 0.77 | KCNA3 (0.46) | ALDH1A1LMNAMAOA | |
| SCHEMBL6467512 | 0.76 | MAOB (0.53) | MAOBSOD1KDM4EALDH1A1RAB9A | |
| SCHEMBL943678 | 0.76 | MAOB (0.56) | MAOBSOD1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL30788655 | 0.76 | MAOB (0.56) | MAOBSOD1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2794321 | 0.75 | MAOB (0.51) | MAOBKDM4EALDH1A1RAB9ALMNA | |
| SCHEMBL29539883 | 0.75 | DRD1 (0.46) | MAOBKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL22904 | 0.75 | DRD1 (0.46) | MAOBKDM4EHSD17B10ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |