Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 9/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL30167549 | 0.95 | GRM5 (0.41) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL986465 | 0.93 | P2RX7 (0.44) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL12194027 | 0.92 | GRM5 (0.45) | PDK4GRM5GRM1NAMPTUSP2 | |
| SCHEMBL20131001 | 0.92 | PDK4 (0.40) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL22539474 | 0.91 | P2RX7 (0.39) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL19373550 | 0.91 | PDK4 (0.39) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL2029150 | 0.90 | USP30 (0.37) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL20998704 | 0.90 | PDK4 (0.41) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL18409255 | 0.90 | PDK4 (0.39) | PDK4GRM5USP30GRM1NAMPT | |
| SCHEMBL10179664 | 0.89 | P2RX7 (0.46) | PDK4USP30P2RX7USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7331 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040434-A | Double-arm TPE derivative with side chains containing mannose molecules and norbornene, and preparation and application thereof | 上海应用技术大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119212999-A | Pyrrolopyrimidine compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-12-27 | — | — | CN | claimed |
| CN-118420882-B | Polymer containing tetraphenyl ethylene and mannose in side chain, preparation method and application thereof | 上海美迪西生物医药股份有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118406174-B | Mannose-containing polymer, method for preparing mannose-containing polymer by combining RAFT polymerization and click chemistry and application thereof | 上海美迪西生物医药股份有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118420882-A | Polymer containing tetraphenyl ethylene and mannose in side chain, preparation method and application thereof | 上海美迪西生物医药股份有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-118406174-A | Mannose-containing polymer, method for preparing mannose-containing polymer by combining RAFT polymerization and click chemistry and application thereof | 上海美迪西生物医药股份有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-117736208-A | Pyrrole [2,3-d ] pyrimidine derivative, and preparation method and application thereof | 四川大学华西医院 | 2024-03-22 | — | — | CN | claimed |
| CN-117164591-A | Pyrrolopyrimidine compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2023-12-05 | — | — | CN | claimed |
| WO-2023226580-A1 | PYRROLOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 中国医学科学院药物研究所 | 2023-11-30 | — | — | WO | claimed |
| CN-110922421-B | Synthesis method of N-methyl-1, 2,5, 6-tetrahydropyridine-4-boric acid pinacol ester | 安徽英特美科技有限公司 | 2023-05-05 | — | — | CN | claimed |
| US-20260144788-A1 | COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2026-05-28 | — | — | US | disclosed |
| US-20260144881-A1 | HPK1 TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2026-05-28 | — | — | US | disclosed |
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| US-12636290-B2 | BET inhibitors for modulating DUX4 expression in FSHD | SAINT LOUIS UNIVERSITY (US) | 2026-05-26 | — | — | US | disclosed |
| US-12636296-B1 | Cannabinol analogs and their use as pharmacologically active agents | NALU BIO, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| WO-2002068388-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002059117-A1 | PIPERAZINE- AND PIPERIDINE-DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |
| US-20020040040-A1 | Substituted 4-phenyl-pyridine compounds with activity as antagonists of neurokinin 1 receptors | F. HOFFMAN-LA ROCHE AG (CH) | 2002-04-04 | — | — | US | disclosed |
| WO-2002016324-A1 | 4-PHENYL-PYRIDINE DERIVATIVES AS NEUROKININ-1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-28 | — | — | WO | disclosed |