Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937978 | 0.89 | PTGDR2 (0.53) | PTGDR2KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL1333540 | 0.84 | PTGDR2 (0.70) | PTGDR2CYP2C19PPARGPPARDPPARA | |
| SCHEMBL1333382 | 0.83 | PTGDR2 (0.57) | PTGDR2SLC6A9SMOKCNQ3KCNQ2 | |
| SCHEMBL5433357 | 0.83 | PTGDR2 (0.57) | PTGDR2SLC6A9SMOKCNQ3KCNQ2 | |
| SCHEMBL1331622 | 0.82 | PTGDR2 (0.48) | PTGDR2ALDH1A1HPGDCYP2C19HSD17B10 | |
| SCHEMBL5390308 | 0.81 | PTGDR2 (0.53) | PTGDR2KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL1332176 | 0.79 | PTGDR2 (0.50) | PTGDR2SLC6A9KCNQ3KCNQ2PPARG | |
| SCHEMBL5387505 | 0.78 | PTGDR2 (0.51) | PTGDR2KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL1333608 | 0.75 | PTGDR2 (0.70) | PTGDR2PPARGPPARDPPARA | |
| SCHEMBL5984297 | 0.75 | TRPV4 (0.45) | PTGDR2KDM4EUSP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |