Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50477 | 0.97 | — | — | |
| SCHEMBL28597552 | 0.97 | TSHR (0.42) | TSHRANPEPADRB2ADRB1ADRB3 | |
| SCHEMBL28009351 | 0.94 | — | — | |
| Alcohol SCHEMBL28122272 | 0.92 | TSHR (0.44) | TSHRANPEPADRB2ADRB1ADRB3 | |
| Tetramethylammonium Ion SCHEMBL8050131 | 0.90 | TSHR (0.37) | TSHRANPEPADRB2ADRB1ADRB3 | |
| SCHEMBL170051 | 0.89 | — | — | |
| SCHEMBL23302194 | 0.86 | THRB (0.44) | TSHRALDH1A1CA1CA2LMNA | |
| Ammonia Solution, Strong SCHEMBL2792661 | 0.86 | CA12 (0.39) | TSHRANPEPCA1CA2MEN1 | |
| Ammonia Solution, Strong SCHEMBL2792659 | 0.86 | CA12 (0.39) | TSHRANPEPCA1CA2MEN1 | |
| SCHEMBL4861420 | 0.86 | THRB (0.44) | TSHRALDH1A1CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4299664-B2 | — | — | 2009-07-22 | — | — | JP | claimed |
| US-7329468-B2 | Multi-layer composites formed from compositions having improved adhesion, coating compositions, and methods related thereto | PPG INDUSTRIES OHIO, INC. (US) | 2008-02-12 | — | — | US | claimed |
| US-20050042463-A1 | Multi-layer composites formed from compositions having improved adhesion, coating compositions, and methods related thereto | ANDERSON LAWRENCE G (US) | 2005-02-24 | — | — | US | claimed |
| JP-2005503938-A | — | — | 2005-02-10 | — | — | JP | claimed |
| EP-1456012-A2 | MULTI-LAYER COMPOSITES FORMED FROM COMPOSITIONS HAVING IMPROVED ADHESION, COATING COMPOSITIONS, AND METHODS RELATED THERETO | PPG Industries Ohio, Inc. (US) | 2004-09-15 | — | — | EP | claimed |
| EP-1417273-A2 | COATING COMPOSITIONS HAVING IMPROVED ADHESION, COATED SUBSTRATES AND METHODS RELATED THERETO | PPG Industries Ohio, Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| US-20030232222-A1 | Multi-layer composites formed from compositions having improved adhesion, coating compositions, and methods related thereto | ANDERSON LAWRENCE G (US) | 2003-12-18 | — | — | US | claimed |
| US-6623791-B2 | Scratch resistant color or clear coatings | PPG INDUSTRIES OHIO, INC. | 2003-09-23 | — | — | US | claimed |
| US-20030118846-A1 | Multi-layer composites formed from compositions having improved adhesion, coating compositions, and methods related thereto | PPG INDUSTRIES OHIO, INC. | 2003-06-26 | — | — | US | claimed |
| WO-2003011583-A2 | MULTI-LAYER COMPOSITES FORMED FROM COMPOSITIONS HAVING IMPROVED ADHESION, COATING COMPOSITIONS, AND METHODS RELATED THERETO | PPG INDUSTRIES OHIO, INC. (US) | 2003-02-13 | — | — | WO | claimed |
| WO-2003011992-A2 | COATING COMPOSITIONS HAVING IMPROVED ADHESION, COATED SUBSTRATES AND METHODS RELATED THERETO | PPG INDUSTRIES OHIO, INC. (US) | 2003-02-13 | — | — | WO | claimed |
| US-20020086168-A1 | Coating compositions having improved adhesion, coated substrates and methods related thereto | PPG INDUSTRIES OHIO, INC. | 2002-07-04 | — | — | US | claimed |