SCHEMBL3935737

SCHEMBL3935737

CN(/N=C/c1ccc[n+](CCCCS(=O)(=O)[O-])c1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.41
EIF4H Q15056 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
MAPT P10636 8/20 0.36
MEN1 O00255 6/20 0.36
KMT2A Q03164 6/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 3/20 0.36
POLB P06746 2/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 4/20 0.35
ALOX12 P18054 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 3/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3935739 1.00 PABPC1 (0.41) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3934798 0.97 PABPC1 (0.44) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3934801 0.97 PABPC1 (0.44) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3942683 0.91 MEN1 (0.37) PABPC1EIF4HCTDSP1MEN1KMT2A
SCHEMBL3942680 0.91 MEN1 (0.37) PABPC1EIF4HCTDSP1MEN1KMT2A
SCHEMBL3944176 0.91 KDM4E (0.36) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3944179 0.91 KDM4E (0.36) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3933439 0.90 PABPC1 (0.34) PABPC1EIF4HCTDSP1MEN1KMT2A
SCHEMBL3933441 0.90 PABPC1 (0.34) PABPC1EIF4HCTDSP1MEN1KMT2A
SCHEMBL3944014 0.90 PABPC1 (0.46) PABPC1EIF4HCTDSP1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847250-B1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes PROCTER & GAMBLE (US) 2009-12-23 EP claimed
US-7513918-B2 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes THE PROCTER & GAMBLE COMPANY (US) 2009-04-07 US claimed
WO-2007119228-A2 AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES THE PROCTER & GAMBLE COMPANY (US) 2007-10-25 WO claimed
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes WELLA OPERATIONS US, LLC 2007-10-25 US claimed
EP-1847250-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-10-24 EP claimed
EP-1847250-B1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes PROCTER & GAMBLE (US) 2009-12-23 EP disclosed
US-7513918-B2 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes THE PROCTER & GAMBLE COMPANY (US) 2009-04-07 US disclosed
EP-1852104-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-11-07 EP disclosed
WO-2007119228-A2 AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES THE PROCTER & GAMBLE COMPANY (US) 2007-10-25 WO disclosed
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes WELLA OPERATIONS US, LLC 2007-10-25 US disclosed
EP-1847250-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes KRT18, IK, RARG PABPC1 3524/4885EIF4H 4790/4885CTDSP1 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.