Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28067757 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Formic Acid SCHEMBL34589 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Formic Acid SCHEMBL27585558 | 0.97 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Formic Acid SCHEMBL4640335 | 0.97 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Formic Acid SCHEMBL5764681 | 0.97 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Formic Acid SCHEMBL28430200 | 0.97 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Methylene Chloride SCHEMBL28132466 | 0.91 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Methylene Chloride SCHEMBL10795300 | 0.86 | KDM4E (0.30) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Acetonitrile SCHEMBL7143866 | 0.86 | CHRM2 (0.32) | ALDH1A1MAPK1TDP1KDM4EMEN1 | |
| Diethylaminoethanol SCHEMBL5027749 | 0.80 | CYP1A2 (0.45) | ALDH1A1MAPK1KDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007747-A2 | HYDANTOIN DERIVATIVES USED AS MMP12 INHIBITORS | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |