⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931948 | 1.00 | — | — | |
| SCHEMBL3935974 | 1.00 | — | — | |
| SCHEMBL18194366 | 0.79 | — | — | |
| SCHEMBL11359696 | 0.73 | — | — | |
| SCHEMBL18642897 | 0.71 | — | — | |
| SCHEMBL18187478 | 0.71 | — | — | |
| SCHEMBL13482981 | 0.70 | MAPK1 (0.41) | — | |
| SCHEMBL29130353 | 0.70 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL29130349 | 0.70 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL6015013 | 0.69 | PRKCA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573277-B | Method for producing 5-hydroxypiperidine-2-carboxylic acid | 株式会社API | 2020-10-16 | — | — | CN | disclosed |
| CN-111499562-A | Method for producing 5-hydroxypiperidine-2-carboxylic acid | 株式会社API | 2020-08-07 | — | — | CN | disclosed |
| WO-2009011551-A2 | PROCESS FOR THE EFFICIENT PREPARATION OF 3-HYDROXY PYRROLIDINE AND DERIVATIVES THEREOF | RSTECH CORPORATION (KR) | 2009-01-22 | — | — | WO | disclosed |