Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935413 | 1.00 | KDM4E (0.68) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL3941759 | 0.93 | KDM4E (0.60) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL13963644 | 0.91 | PLA2G2A (0.59) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL3936021 | 0.90 | PLA2G2A (0.65) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL13963326 | 0.90 | PLA2G2A (0.58) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL4602262 | 0.90 | KDM4E (0.68) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL13958696 | 0.88 | PLA2G2A (0.59) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL4602317 | 0.88 | KDM4E (0.66) | KDM4EHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3937571 | 0.86 | KDM4E (0.64) | KDM4EHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4600479 | 0.86 | DHODH (0.64) | KDM4EPLA2G2AHSD17B10SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013354-A1 | ARYLMETHYLENE SUBSTITUTED N-ACYL-β-AMINO ALCOHOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-01-29 | — | — | WO | disclosed |