⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798054 | 1.00 | — | — | |
| SCHEMBL11513295 | 0.78 | TSHR (0.55) | — | |
| SCHEMBL12703543 | 0.78 | TSHR (0.61) | — | |
| SCHEMBL462297 | 0.77 | — | — | |
| SCHEMBL27380 | 0.75 | TSHR (1.00) | — | |
| SCHEMBL5311581 | 0.75 | TSHR (1.00) | — | |
| SCHEMBL177923 | 0.75 | TSHR (0.67) | — | |
| SCHEMBL9795394 | 0.73 | TSHR (0.94) | — | |
| SCHEMBL10317949 | 0.73 | TSHR (0.94) | — | |
| Methane SCHEMBL11192510 | 0.73 | TSHR (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003815-A | SG2C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | claimed |
| CN-117003822-A | SG3C bromobenzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2023-11-07 | — | — | CN | claimed |
| CN-115106085-B | Application of composite photocatalyst in photocatalytic oxidation of aromatic alcohol coupling hydrogen | 中国科学院理化技术研究所 | 2023-09-15 | — | — | CN | claimed |
| CN-115106085-A | Application of composite photocatalyst in photocatalytic oxidation aromatic alcohol coupling hydrogen production | 中国科学院理化技术研究所 | 2022-09-27 | — | — | CN | claimed |
| CN-111943876-B | N2S2 bromo-benzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2022-04-19 | — | — | CN | claimed |
| CN-109195960-B | Bromo-benzyl ether derivative, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-05-04 | — | — | CN | claimed |
| CN-111943876-A | N2S2 bromo-benzyl ether derivative, preparation method and application | 江苏省原子医学研究所 | 2020-11-17 | — | — | CN | claimed |
| EP-3246328-B1 | QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2020-07-22 | — | — | EP | claimed |
| CN-109195960-A | Bromo benzyl oxide derivative and its preparation method and pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2019-01-11 | — | — | CN | claimed |
| US-10106508-B2 | Quinazoline heterocyclic compound as EGFR kinase inhibitor and preparation and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2018-10-23 | — | — | US | claimed |
| CN-103694197-B | Phenoxyacetamide compound and preparation method and application thereof | UNIV HUAZHONG NORMAL | 2015-07-15 | — | — | CN | claimed |
| EP-2831027-A1 | A PROCESS FOR SEPARATING ARYL CARBOXYLIC ACIDS | Reliance Industries Limited (IN) | 2015-02-04 | — | — | EP | claimed |
| CN-104254513-A | Process for separating aryl carboxylic acid | RELIANCE IND LTD | 2014-12-31 | — | — | CN | claimed |
| CN-104109115-A | Phenylpropionic acid compounds chained by nitrogen-containing heterocyclic rings, pharmaceutical composition, preparation method, and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-10-22 | — | — | CN | claimed |
| CN-103694197-A | Phenoxyacetamide compound and preparation method and application thereof | UNIV HUAZHONG NORMAL | 2014-04-02 | — | — | CN | claimed |
| WO-2013164852-A1 | A PROCESS FOR SEPARATING ARYL CARBOXYLIC ACIDS | RELIANCE INDUSTRIES LIMITED (IN) | 2013-11-07 | — | — | WO | claimed |
| CN-101952233-B | Method of making benzylated phenols | SABIC INNOVATIVE PLASTICS IP | 2012-12-05 | — | — | CN | claimed |
| CN-101952233-A | Method of making benzylated phenols | GEN ELECTRIC | 2011-01-19 | — | — | CN | claimed |
| CN-100355772-C | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2007-12-19 | — | — | CN | claimed |
| CN-1793164-A | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2006-06-28 | — | — | CN | claimed |