Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936616 | 0.94 | AOC3 (0.49) | AOC3CLK1 | |
| SCHEMBL3934271 | 0.90 | AOC3 (0.60) | AOC3 | |
| SCHEMBL4877656 | 0.88 | AOC3 (0.52) | AOC3CLK1 | |
| Hydrochloric Acid SCHEMBL3942951 | 0.87 | AOC3 (0.48) | AOC3 | |
| SCHEMBL4875403 | 0.85 | AOC3 (0.53) | AOC3CLK1 | |
| SCHEMBL3939586 | 0.84 | AOC3 (0.42) | AOC3 | |
| Carbamic Acid SCHEMBL3939590 | 0.83 | AOC3 (0.46) | AOC3 | |
| SCHEMBL5496060 | 0.82 | AOC3 (0.47) | AOC3 | |
| Hydrochloric Acid SCHEMBL3934265 | 0.82 | AOC3 (0.48) | AOC3 | |
| SCHEMBL5545487 | 0.81 | AOC3 (0.40) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-B1 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | ASTELLAS PHARMA INC. (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | VCAM1, VAPB, VAPA | AOC3 386/4885CLK1 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.