Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757493 | 0.86 | L3MBTL1 (0.38) | L3MBTL1TSHRKDM4EAHRNPC1 | |
| SCHEMBL264016 | 0.75 | KDM4E (0.49) | L3MBTL1TSHRKDM4EAHRNPC1 | |
| SCHEMBL8066761 | 0.73 | L3MBTL1 (0.44) | L3MBTL1TSHRKDM4EAHRNPC1 | |
| SCHEMBL18233765 | 0.71 | MAOB (0.41) | L3MBTL1TSHRKDM4EAHRNPC1 | |
| SCHEMBL3979225 | 0.68 | MAPT (0.41) | L3MBTL1TSHRKDM4EAHRNPC1 | |
| SCHEMBL7617407 | 0.68 | CA1 (0.46) | TSHRKDM4ENPC1MAPTRAB9A | |
| SCHEMBL3021187 | 0.67 | CA12 (0.48) | L3MBTL1TSHRKDM4EMAPTHPGD | |
| SCHEMBL1257007 | 0.67 | MAPT (0.50) | L3MBTL1TSHRKDM4EAHRNPC1 | |
| SCHEMBL2719076 | 0.65 | CA12 (0.42) | L3MBTL1TSHRKDM4EMAPTHPGD | |
| SCHEMBL21854494 | 0.65 | GLP1R (0.46) | L3MBTL1TSHRKDM4EAHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046781-A2 | SUBSTITUTED FURYL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLINE(THI)ONES | Bayer CropScience AG (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008006499-A2 | SUBSTITUTED FURYL SULFONYLAMINO(THIO)CARBONYL TRIAZOLINE(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |