Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932131 | 0.90 | CCR5 (0.51) | CCR5SMN1; SMN2 | |
| SCHEMBL3934113 | 0.82 | CCR5 (0.66) | CCR5 | |
| SCHEMBL3928637 | 0.81 | PTGDR2 (0.59) | CCR5PTGDR2 | |
| SCHEMBL3936203 | 0.81 | CCR5 (0.57) | CCR5PTGDR2 | |
| SCHEMBL3927273 | 0.81 | CCR5 (0.57) | CCR5PTGDR2 | |
| SCHEMBL3928972 | 0.81 | CCR5 (0.69) | CCR5 | |
| SCHEMBL4012562 | 0.80 | CCR5 (0.56) | CCR5PTGDR2 | |
| SCHEMBL3928105 | 0.80 | CCR5 (0.72) | CCR5 | |
| SCHEMBL3933237 | 0.80 | CCR5 (0.56) | CCR5PTGDR2 | |
| SCHEMBL3932052 | 0.79 | CCR5 (0.55) | CCR5PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |