Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138875 | 0.91 | CYP3A4 (0.75) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL3944098 | 0.91 | CYP3A4 (0.75) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL29642680 | 0.91 | CYP3A4 (0.75) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL8838333 | 0.89 | CYP3A4 (0.73) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL7332204 | 0.89 | CYP3A4 (0.73) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| Piperonylic Acid SCHEMBL142318 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| Piperonylic Acid SCHEMBL31119409 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| Piperonylic Acid SCHEMBL3946119 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| Piperonylic Acid SCHEMBL1184937 | 0.84 | ALDH1A1 (0.96) | ALDH1A1MAPK1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL2957608 | 0.83 | CYP3A4 (0.65) | ALDH1A1CYP3A4CYP1A2CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009017848-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES SUCH AS SYSTEMIC AA AMYLOIDOSIS | PROTEO TECH INC (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009017848-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES SUCH AS SYSTEMIC AA AMYLOIDOSIS | PROTEO TECH INC. (US) | 2009-02-05 | — | — | WO | disclosed |