Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555445 | 0.92 | HTR6 (0.48) | HTR6KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL14953611 | 0.91 | HTR6 (0.42) | HTR6HTR7 | |
| SCHEMBL3554474 | 0.91 | HTR6 (0.43) | HTR6KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL3561748 | 0.90 | HTR6 (0.43) | HTR6KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL3559688 | 0.90 | HTR6 (0.43) | HTR6 | |
| SCHEMBL3552978 | 0.89 | HTR6 (0.53) | HTR6KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL3936199 | 0.89 | HTR6 (0.43) | HTR6KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL6112280 | 0.86 | HTR6 (0.36) | HTR6SMN1; SMN2 | |
| SCHEMBL3560606 | 0.85 | HTR6 (0.48) | HTR6KDM4EALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL3555567 | 0.83 | HTR6 (0.53) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | claimed |
| US-7507835-B2 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD. (IN) | 2009-03-24 | — | — | US | claimed |