SCHEMBL393714

SCHEMBL393714

C=CCCCCC(=CC)CCC=C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
ABCC4 O15439 1/20 0.46
ALDH1A1 P00352 3/20 0.45
LMNA P02545 2/20 0.45
TSHR P16473 3/20 0.42
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32
TRPA1 O75762 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395384 0.98 MAPT (0.50) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL14481454 0.93 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL393910 0.93 MAPT (0.54) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL29047256 0.85 TSHR (0.60) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL848258 0.84 TSHR (0.46) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL848257 0.84 TSHR (0.46) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL846699 0.82 TSHR (0.50) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL846700 0.82 TSHR (0.50) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL2066529 0.82 TSHR (0.50) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL2066527 0.82 TSHR (0.50) MAPTABCC4ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0940448-B1 Reinforced composition DEGUSSA (DE) 2005-03-09 EP claimed
EP-0940439-B1 use of crosslinkable mouldings for producing moulded bodies DEGUSSA (DE) 2004-04-07 EP claimed
US-20150322314-A1 Moisture-Curing Polyurethane Composition Comprising Sustainably Produced Raw Materials HENKEL AG & CO. KGAA (DE) 2015-11-12 US disclosed
US-8101681-B2 Prepolymer mixture containing silyl groups and use thereof HENKEL AG & CO. KGAA (DE) 2012-01-24 US disclosed
US-20090306283-A1 PREPOLYMER MIXTURE CONTAINING SILYL GROUPS AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2009-12-10 US disclosed
US-6583253-B1 Films, fibers and moldings, heat sealable coating materials; metallocene catalyst BASELL POLYPROPYLEN GMBH (DE) 2003-06-24 US disclosed