Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14481454 | 1.00 | MAPT (0.54) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL395384 | 0.95 | MAPT (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL393714 | 0.93 | MAPT (0.46) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL29047256 | 0.91 | TSHR (0.60) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL2066529 | 0.89 | TSHR (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3447108 | 0.89 | TSHR (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL846699 | 0.89 | TSHR (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3447109 | 0.89 | TSHR (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL2066527 | 0.89 | TSHR (0.50) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL846700 | 0.89 | TSHR (0.50) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940448-B1 | Reinforced composition | DEGUSSA (DE) | 2005-03-09 | — | — | EP | claimed |
| US-20150322314-A1 | Moisture-Curing Polyurethane Composition Comprising Sustainably Produced Raw Materials | HENKEL AG & CO. KGAA (DE) | 2015-11-12 | — | — | US | disclosed |
| US-8101681-B2 | Prepolymer mixture containing silyl groups and use thereof | HENKEL AG & CO. KGAA (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20090306283-A1 | PREPOLYMER MIXTURE CONTAINING SILYL GROUPS AND USE THEREOF | HENKEL AG & CO. KGAA (DE) | 2009-12-10 | — | — | US | disclosed |