Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123913 | 0.66 | KDM1A (0.31) | — | |
| SCHEMBL4583165 | 0.65 | — | — | |
| SCHEMBL29603260 | 0.65 | — | — | |
| SCHEMBL9480647 | 0.61 | MAPT (0.32) | MAPT | |
| SCHEMBL31255990 | 0.61 | KDM1A (0.33) | — | |
| SCHEMBL14879909 | 0.61 | ESR2 (0.31) | — | |
| SCHEMBL15075584 | 0.61 | MAPT (0.33) | MAPT | |
| SCHEMBL15059552 | 0.61 | MAPT (0.33) | MAPT | |
| SCHEMBL5613948 | 0.61 | — | — | |
| SCHEMBL785509 | 0.61 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016565-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2009-02-05 | — | — | WO | claimed |
| WO-2009016565-A1 | TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2009-02-05 | — | — | WO | disclosed |