SCHEMBL785509

SCHEMBL785509

O=C1CC2CCCC=C2O1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CTRB1 P17538 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5669497 0.88
SCHEMBL3235164 0.82 MAPT (0.35) MAPT
SCHEMBL31696779 0.72
SCHEMBL8103298 0.67 MAPT (0.30) MAPT
SCHEMBL7401293 0.64
SCHEMBL662813 0.64 MAPT (0.40) MAPT
SCHEMBL1986436 0.64
SCHEMBL2521267 0.64
SCHEMBL1711999 0.63
SCHEMBL3234841 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230202996-A1 SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES P2 SCIENCE, INC. 2023-06-29 US claimed
WO-2023122724-A1 IMPROVED SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES P2 SCIENCE, INC. (US) 2023-06-29 WO claimed
US-5114493-A Smoking compositions containing a hexahydrobenzofuranone flavorant PHILIP MORRIS INC. (US) 1992-05-19 US claimed
US-4407740-A Di- and Tetra-hydrobenzofuranones as scents and aroma substances HAARMANN & REIMER GMBH (DE) 1983-10-04 US claimed
JP-1290627-A None JP disclosed
JP-7101952-A None JP disclosed
EP-3856734-B1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2025-09-24 EP disclosed
CN-118985971-A Preparation method of hawthorn extract for cigarettes and application of hawthorn extract in cigarettes 河南中烟工业有限责任公司 2024-11-22 CN disclosed
US-12065422-B2 Reagents and process for direct C—H functionalization STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2024-08-20 US disclosed
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-07-20 US disclosed
WO-2023122724-A1 IMPROVED SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES P2 SCIENCE, INC. (US) 2023-06-29 WO disclosed
US-20230202996-A1 SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES P2 SCIENCE, INC. 2023-06-29 US disclosed
US-5114493-A Smoking compositions containing a hexahydrobenzofuranone flavorant PHILIP MORRIS INC. (US) 1992-05-19 US disclosed
US-5114493-A Smoking compositions containing a hexahydrobenzofuranone flavorant PHILIP MORRIS INC. (US) 1992-05-19 US disclosed
JP-H01290627-A ANTITUMOR AGENT MITSUBISHI KASEI CORP 1989-11-22 JP disclosed
US-4407740-A Di- and Tetra-hydrobenzofuranones as scents and aroma substances HAARMANN & REIMER GMBH (DE) 1983-10-04 US disclosed
US-4407740-A Di- and Tetra-hydrobenzofuranones as scents and aroma substances HAARMANN & REIMER GMBH (DE) 1983-10-04 US disclosed
US-4407740-A Di- and Tetra-hydrobenzofuranones as scents and aroma substances HAARMANN & REIMER GMBH (DE) 1983-10-04 US disclosed
US-4119646-A Hexahydrobenzofuranone compounds MOBIL OIL CORPORATION (US) 1978-10-10 US disclosed
US-4119646-A Hexahydrobenzofuranone compounds MOBIL OIL CORPORATION (US) 1978-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227425-A1 REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION CFH, DOHH, CTSH MAPT 3465/4885CTRB1 893/4885
US-20230202996-A1 SYNTHETIC METHODS FOR MAKING CARBOXYLIC ACIDS, ESTERS AND LACTONES FDFT1, DLST, PCMT1 MAPT 1409/4885CTRB1 3473/4885
US-12065422-B2 Reagents and process for direct C—H functionalization CFH, DOHH, CTSH MAPT 3330/4885CTRB1 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.