SCHEMBL3937601

SCHEMBL3937601

NC(=O)COC(=O)[C@@H](N)CS

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
CPN1 P15169 1/20 0.32
CPB2 Q96IY4 1/20 0.32
ENPEP Q07075 4/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 3/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.31
GLA P06280 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
APEX1 P27695 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1893431 0.82 PTGS1 (0.52) PTGS1SLC7A11CPN1CPB2ENPEP
SCHEMBL197220 0.82 PTGS1 (0.52) PTGS1SLC7A11CPN1CPB2ENPEP
SCHEMBL8751954 0.78
SCHEMBL5904020 0.76
SCHEMBL28437975 0.76
SCHEMBL1964879 0.75 PTGS1 (0.55) PTGS1SLC7A11CPB2ENPEPANPEP
SCHEMBL462748 0.75 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEP
SCHEMBL20657045 0.75 PTGS1 (0.55) PTGS1SLC7A11CPB2ENPEPANPEP
SCHEMBL8003523 0.75 PTGS1 (0.40) PTGS1SLC7A11ENPEPKDM4ELMNA
SCHEMBL6891065 0.74 PTGS1 (0.48) PTGS1SLC7A11ENPEPANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118962144-A Determining prognosis of cancer 昆士兰医学研究所理事会 2024-11-15 CN disclosed
CN-110168373-B Determining prognosis of cancer 昆士兰医学研究所理事会 2024-06-21 CN disclosed
CN-114380909-A Antibodies specific for glycosylated PD-L1 and methods of use thereof 斯特库比股份有限公司 2022-04-22 CN disclosed
CN-107530429-B Antibodies specific for glycosylated PD-L1 and methods of use thereof 斯特库比股份有限公司 2021-12-07 CN disclosed
CN-111263886-A Multimicrosphere arrays for proteomics 阿德普特里克斯公司 2020-06-09 CN disclosed
CN-102460161-B Method for being transferred to polypeptide in cell 洛菲厄斯生物科学有限责任公司 2017-08-29 CN disclosed
WO-2015042704-A1 BIOMARKERS FOR MYCOBACTERIUM AVIUM PARATUBERCULOSIS (MAP) UNIVERSITY OF GUELPH (CA) 2015-04-02 WO disclosed
WO-2009018307-A2 ANALYSIS OF POLYPEPTIDE PRODUCTION WYETH (US) 2009-02-05 WO disclosed