SCHEMBL462748

SCHEMBL462748

N[C@@H](CS)C(=O)OOC(=O)[C@@H](N)CS

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 1/20 0.55
▸ SLC7A11 Q9UPY5 1/20 0.55
▸ ENPEP Q07075 12/20 0.37
▸ ANPEP P15144 6/20 0.36
▸ MMP2 P08253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29120022 0.97 PTGS1 (0.52) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL16269970 0.85 — —
SCHEMBL1964879 0.83 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL20657045 0.83 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL25418591 0.81 — —
Hydrochloric Acid SCHEMBL11053789 0.81 PTGS1 (0.52) PTGS1SLC7A11ENPEPANPEPMMP2
Hydrochloric Acid SCHEMBL11053790 0.81 PTGS1 (0.52) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL8751954 0.81 — —
SCHEMBL60257 0.81 — —
SCHEMBL17966747 0.81 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3429573-A1 COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS Thiogenesis Therapeutics, Inc. (US) 2019-01-23 — — EP claimed
WO-2017161318-A1 COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS THIOGENESIS THERAPEUTICS, INC. (US) 2017-09-21 — — WO claimed
US-5316767-A Oligopeptide; water soluble, heat resistance, stability KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-05-31 — — US claimed
US-12569456-B2 Methods for the treatment of cysteamine sensitive disorders THIOGENESIS THERAPEUTICS, INC. (US) 2026-03-10 — — US disclosed
US-20250170253-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS ENDOCYTE INC (US) 2025-05-29 — — US disclosed
EP-4534527-A2 METHODS FOR THE TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS Thiogenesis Therapeutics, Inc. (US) 2025-04-09 — — EP disclosed
CN-119630280-A Compositions and methods for preventing, treating, inhibiting and/or eliminating phytopathogenic infestations and infections 诺维信公司 2025-03-14 — — CN disclosed
EP-3684418-B1 COMPOUNDS FOR THE TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS THIOGENESIS THERAPEUTICS INC (US) 2025-02-12 — — EP disclosed
CN-118924717-A Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-11-12 — — CN disclosed
CN-111683684-B Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-07-02 — — CN disclosed
CN-118225951-A Marker group for major depressive disorder and screening method and application thereof 上海大学 2024-06-21 — — CN disclosed
US-20160296630-A1 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES ENDOCYTE INC (US) 2016-10-13 — — US disclosed
US-20150297735-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS ENDOCYTE, INC. 2015-10-22 — — US disclosed
EP-2919774-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS Endocyte, Inc. (US) 2015-09-23 — — EP disclosed
US-20140154702-A1 Methods For Treating Cancer Using Combination Therapies ENDOCYTE INC (US) 2014-06-05 — — US disclosed
WO-2014085575-A1 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES ENDOCYTE, INC. (US) 2014-06-05 — — WO disclosed
WO-2014078484-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS ENDOCYTE, INC. (US) 2014-05-22 — — WO disclosed
CN-102834110-A Methods and compositions using peroxiredoxin 1 (PRX1) as an adjuvant HEALTH RESEARCH INC 2012-12-19 — — CN disclosed
US-20120022161-A1 ACETYCYSTEINE COMPOSITIONS AND METHODS OF USE THEREOF CUMBERLAND PHARMACEUTICALS, INC. (US) 2012-01-26 — — US disclosed
EP-0399555-A2 A feed composition for culturing fishes KYOWA HAKKO KOGYO CO., LTD. (JP) 1990-11-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569456-B2 Methods for the treatment of cysteamine sensitive disorders SLC7A11, CTH, SLC19A1 PTGS1 365/4885SLC7A11 1/4885ENPEP 80/4885
US-20160296630-A1 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES SLC7A11, CXCR2, TPX2 PTGS1 304/4885SLC7A11 1/4885ENPEP 174/4885
US-20250170253-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS FOLH1, KLK3, CD47 PTGS1 3280/4885SLC7A11 187/4885ENPEP 6/4885
US-20150297735-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS FOLH1, KLK3, CD47 PTGS1 3280/4885SLC7A11 187/4885ENPEP 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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