SCHEMBL462748

SCHEMBL462748

N[C@@H](CS)C(=O)OOC(=O)[C@@H](N)CS

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.55
SLC7A11 Q9UPY5 1/20 0.55
ENPEP Q07075 12/20 0.37
ANPEP P15144 6/20 0.36
MMP2 P08253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29120022 0.97 PTGS1 (0.52) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL16269970 0.85
SCHEMBL20657045 0.83 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL1964879 0.83 PTGS1 (0.55) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL25418591 0.81
SCHEMBL60257 0.81
SCHEMBL17966747 0.81
Hydrochloric Acid SCHEMBL11053790 0.81 PTGS1 (0.52) PTGS1SLC7A11ENPEPANPEPMMP2
Hydrochloric Acid SCHEMBL11053789 0.81 PTGS1 (0.52) PTGS1SLC7A11ENPEPANPEPMMP2
SCHEMBL8751954 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3429573-A1 COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS Thiogenesis Therapeutics, Inc. (US) 2019-01-23 EP claimed
WO-2017161318-A1 COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS THIOGENESIS THERAPEUTICS, INC. (US) 2017-09-21 WO claimed
US-5316767-A Oligopeptide; water soluble, heat resistance, stability KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-05-31 US claimed
US-12569456-B2 Methods for the treatment of cysteamine sensitive disorders THIOGENESIS THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20250170253-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS ENDOCYTE INC (US) 2025-05-29 US disclosed
EP-4534527-A2 METHODS FOR THE TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS Thiogenesis Therapeutics, Inc. (US) 2025-04-09 EP disclosed
CN-119630280-A Compositions and methods for preventing, treating, inhibiting and/or eliminating phytopathogenic infestations and infections 诺维信公司 2025-03-14 CN disclosed
EP-3684418-B1 COMPOUNDS FOR THE TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS THIOGENESIS THERAPEUTICS INC (US) 2025-02-12 EP disclosed
CN-118924717-A Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-11-12 CN disclosed
CN-111683684-B Methods for treating cysteamine-sensitive disorders 硫创治疗公司 2024-07-02 CN disclosed
CN-118225951-A Marker group for major depressive disorder and screening method and application thereof 上海大学 2024-06-21 CN disclosed
US-20160296630-A1 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES ENDOCYTE INC (US) 2016-10-13 US disclosed
US-20150297735-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS ENDOCYTE, INC. 2015-10-22 US disclosed
EP-2919774-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS Endocyte, Inc. (US) 2015-09-23 EP disclosed
US-20140154702-A1 Methods For Treating Cancer Using Combination Therapies ENDOCYTE INC (US) 2014-06-05 US disclosed
WO-2014085575-A1 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES ENDOCYTE, INC. (US) 2014-06-05 WO disclosed
WO-2014078484-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS ENDOCYTE, INC. (US) 2014-05-22 WO disclosed
CN-102834110-A Methods and compositions using peroxiredoxin 1 (PRX1) as an adjuvant HEALTH RESEARCH INC 2012-12-19 CN disclosed
US-20120022161-A1 ACETYCYSTEINE COMPOSITIONS AND METHODS OF USE THEREOF CUMBERLAND PHARMACEUTICALS, INC. (US) 2012-01-26 US disclosed
EP-0399555-A2 A feed composition for culturing fishes KYOWA HAKKO KOGYO CO., LTD. (JP) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569456-B2 Methods for the treatment of cysteamine sensitive disorders SLC7A11, CTH, SLC19A1 PTGS1 365/4885SLC7A11 1/4885ENPEP 80/4885
US-20160296630-A1 METHODS FOR TREATING CANCER USING COMBINATION THERAPIES SLC7A11, CXCR2, TPX2 PTGS1 304/4885SLC7A11 1/4885ENPEP 174/4885
US-20250170253-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS FOLH1, KLK3, CD47 PTGS1 3280/4885SLC7A11 187/4885ENPEP 6/4885
US-20150297735-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS FOLH1, KLK3, CD47 PTGS1 3280/4885SLC7A11 187/4885ENPEP 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.