Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 13/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937983 | 1.00 | NPC1 (0.44) | NPC1RAB9AMEN1HTTKMT2A | |
| Iodide SCHEMBL5918621 | 0.99 | MEN1 (0.46) | NPC1RAB9AMEN1HTTKMT2A | |
| Iodide SCHEMBL5918618 | 0.99 | MEN1 (0.46) | NPC1RAB9AMEN1HTTKMT2A | |
| SCHEMBL3941898 | 0.89 | MEN1 (0.34) | NPC1RAB9AMEN1HTTKMT2A | |
| SCHEMBL3941892 | 0.89 | MEN1 (0.34) | NPC1RAB9AMEN1HTTKMT2A | |
| Iodide SCHEMBL5918663 | 0.88 | MEN1 (0.35) | NPC1RAB9AMEN1HTTKMT2A | |
| Iodide SCHEMBL5918658 | 0.88 | MEN1 (0.35) | NPC1RAB9AMEN1HTTKMT2A | |
| SCHEMBL13052529 | 0.86 | CYP2D6 (0.42) | NPC1RAB9AMEN1HTTKMT2A | |
| SCHEMBL18034219 | 0.86 | ALDH1A1 (0.42) | NPC1RAB9AMEN1HTTKMT2A | |
| SCHEMBL26023228 | 0.85 | CYP2D6 (0.41) | NPC1RAB9AMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609459-B1 | Use of polycationic compounds for dyeing keratinous fibers | OREAL (FR) | 2009-04-08 | — | — | EP | disclosed |
| EP-1609459-A1 | Use of polycationic compounds for dyeing keratinous fibers | L'OREAL (FR) | 2005-12-28 | — | — | EP | disclosed |