Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2785089 | 0.98 | HIF1A (0.36) | HIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL1412809 | 0.98 | HIF1A (0.36) | HIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL1412734 | 0.98 | HIF1A (0.36) | HIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL4639378 | 0.98 | HIF1A (0.36) | HIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL4641195 | 0.98 | HIF1A (0.36) | HIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL1412670 | 0.98 | HIF1A (0.36) | HIF1AEPAS1 | |
| SCHEMBL4067197 | 0.98 | HIF1A (0.34) | HIF1AEPAS1LMNA | |
| SCHEMBL5302232 | 0.97 | HIF1A (0.36) | HIF1AEPAS1LMNA | |
| SCHEMBL5074274 | 0.97 | HIF1A (0.36) | HIF1AEPAS1LMNA | |
| SCHEMBL2774591 | 0.97 | HIF1A (0.36) | HIF1AEPAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2047273-A1 | METHOD AND REAGENT MIXTURE TO MAKE AMINO ACIDS AND PEPTIDES VISIBLE | Merck Patent GmbH (DE) | 2009-04-15 | — | — | EP | claimed |
| WO-2008014859-A1 | METHOD AND REAGENT MIXTURE TO MAKE AMINO ACIDS AND PEPTIDES VISIBLE | MERCK PATENT GMBH (DE) | 2008-02-07 | — | — | WO | claimed |