Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 10/20 | 0.65 |
| ▸ | CCR8 | P51685 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599975 | 0.90 | CCR8 (0.58) | CHRM4CCR8BCHEACHECCR3 | |
| SCHEMBL2967113 | 0.85 | CHRM4 (0.54) | CHRM4CCR8BCHEACHE | |
| SCHEMBL3946316 | 0.85 | CHRM4 (0.69) | CHRM4 | |
| SCHEMBL3591109 | 0.83 | CCR8 (0.71) | CCR8CCR3 | |
| SCHEMBL3940943 | 0.82 | CHRM4 (0.57) | CHRM4BCHEACHE | |
| SCHEMBL3937764 | 0.82 | CHRM4 (0.57) | CHRM4ACHE | |
| SCHEMBL27654951 | 0.79 | CHRM4 (0.50) | CHRM4CCR8 | |
| SCHEMBL3938442 | 0.79 | CHRM4 (0.66) | CHRM4ACHE | |
| SCHEMBL6500525 | 0.79 | CCR8 (0.88) | CCR8CCR3 | |
| SCHEMBL18825716 | 0.78 | CHRM4 (1.00) | CHRM4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |