Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942812 | 0.90 | CHRM4 (0.55) | CHRM4ACHEBCHE | |
| SCHEMBL3946316 | 0.89 | CHRM4 (0.69) | CHRM4CHRM2CHRM1 | |
| SCHEMBL2983017 | 0.85 | CHRM4 (0.50) | CHRM4CHRM2CHRM1ACHEBCHE | |
| SCHEMBL3938451 | 0.82 | CHRM4 (0.65) | CHRM4ACHEBCHE | |
| SCHEMBL3583996 | 0.80 | CHRM4 (0.68) | CHRM4CHRM2CHRM1 | |
| SCHEMBL5709492 | 0.79 | CHRM4 (0.61) | CHRM4CHRM2CHRM1 | |
| SCHEMBL3938442 | 0.79 | CHRM4 (0.66) | CHRM4CHRM2CHRM1ACHE | |
| SCHEMBL3946379 | 0.79 | MCHR1 (0.63) | ACHE | |
| SCHEMBL2980349 | 0.77 | CHRM4 (0.51) | CHRM4CHRM2ACHEBCHE | |
| SCHEMBL5709518 | 0.77 | OPRM1 (0.52) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |