Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726397 | 0.74 | — | — | |
| SCHEMBL434612 | 0.72 | CA12 (0.43) | ALDH1A1TSHRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2838452 | 0.71 | — | — | |
| SCHEMBL12403539 | 0.70 | TSHR (0.42) | ALDH1A1TSHRLMNALPAR3LPAR2 | |
| SCHEMBL26247941 | 0.70 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL433380 | 0.70 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2HPGD | |
| SCHEMBL16130357 | 0.70 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2HPGD | |
| SCHEMBL4725795 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAUSP2CYP3A4 | |
| SCHEMBL29220317 | 0.68 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNAUSP2CYP3A4 | |
| SCHEMBL5023074 | 0.68 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNAUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044081-A2 | IMPROVED OXIDATION PROCESS WITH ENHANCED SAFETY USEFUL IN THE MANUFACTURE OF MOXIDECTIN BY MEANS OF STABILISED 2-IODOXYBENZOIC ACID (SIBX) | Wyeth (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007149305-A2 | IMPROVED OXIDATION PROCESS WITH ENHANCED SAFETY USEFUL IN THE MANUFACTURE OF MOXIDECTIN BY MEANS OF STABILISED 2-IODOXYBENZOIC ACID (SIBX) | WYETH (US) | 2007-12-27 | — | — | WO | disclosed |