Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939736 | 1.00 | SLC6A9 (0.75) | SLC6A9SLC6A5 | |
| SCHEMBL1105669 | 0.85 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL30510966 | 0.85 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL1096822 | 0.85 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL9882745 | 0.85 | SLC6A9 (0.81) | SLC6A9SLC6A5 | |
| SCHEMBL3872901 | 0.85 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL8262322 | 0.83 | SLC6A9 (0.83) | SLC6A9SLC6A5 | |
| SCHEMBL3872141 | 0.83 | SLC6A9 (0.83) | SLC6A9SLC6A5 | |
| SCHEMBL3874228 | 0.83 | SLC6A9 (0.78) | SLC6A9SLC6A5 | |
| SCHEMBL3872067 | 0.83 | SLC6A9 (0.78) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848694-B1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | HOFFMANN LA ROCHE (CH) | 2009-11-25 | — | — | EP | disclosed |
| EP-1848694-A1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | F. Hoffmann-Roche AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006082001-A1 | HETEROCYCLIC SUBSTITUTED PHENYL METHANONES AS INHIBITORS OF THE GLYCINE TRANSPORTER 1 | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | disclosed |