Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.73 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL8075061 | 1.00 | PTGS1 (0.73) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL8585456 | 0.89 | PTGS1 (0.57) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL27480201 | 0.89 | PTGS1 (0.57) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL9621379 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL5218619 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL25292211 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL7270341 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL1819440 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL11344868 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 | |
| Cysteine SCHEMBL5218612 | 0.85 | PTGS1 (0.89) | PTGS1SLC7A11GRIK1GRIK2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090035807-A1 | ANALYSIS OF POLYPEPTIDE PRODUCTION | WYETH (US) | 2009-02-05 | — | — | US | disclosed |
| WO-2009018307-A2 | ANALYSIS OF POLYPEPTIDE PRODUCTION | WYETH (US) | 2009-02-05 | — | — | WO | disclosed |
| CN-1092264-C | Chemically accelerated protein heat treatment | COMMW SCIENT IND RES ORG (AU) | 2002-10-09 | — | — | CN | disclosed |
| EP-0787228-A4 | CHEMICALLY ASSISTED PROTEIN ANNEALING TREATMENT | COMMW SCIENT IND RES ORG (AU) | 1998-09-02 | — | — | EP | disclosed |
| CN-1161067-A | Chemically accelerated protein heat treatment | COMMW SCIENT IND RES ORG (AU) | 1997-10-01 | — | — | CN | disclosed |
| EP-0787228-A1 | CHEMICALLY ASSISTED PROTEIN ANNEALING TREATMENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012057-A1 | CHEMICALLY ASSISTED PROTEIN ANNEALING TREATMENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1996-04-25 | — | — | WO | disclosed |