Cysteine

Cysteine

SCHEMBL27480201

C=C(N)C(=O)O.NC(CS)C(=O)O.NC(CSCC(N)C(=O)O)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.57
SLC7A11 Q9UPY5 1/20 0.57
ARG1 P05089 1/20 0.43
ARG2 P78540 1/20 0.43
NOS2 P35228 6/20 0.42
NOS1 P29475 3/20 0.42
NOS3 P29474 2/20 0.42
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41
GRM1 Q13255 1/20 0.41
GRM2 Q14416 1/20 0.41
ALOX15 P16050 2/20 0.34
ENPEP Q07075 2/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cysteine SCHEMBL8585456 1.00 PTGS1 (0.57) PTGS1SLC7A11ARG1ARG2NOS2
SCHEMBL27932283 0.91 ARG1 (0.50) PTGS1SLC7A11ARG1ARG2NOS2
SCHEMBL1553985 0.91 ARG1 (0.50) PTGS1SLC7A11ARG1ARG2NOS2
Cysteine SCHEMBL8075061 0.89 PTGS1 (0.73) PTGS1SLC7A11NOS2GRIK1GRIK2
Cysteine SCHEMBL3940040 0.89 PTGS1 (0.73) PTGS1SLC7A11NOS2GRIK1GRIK2
Cystine SCHEMBL457219 0.81 PTGS1 (0.73) PTGS1SLC7A11ARG1ARG2NOS2
Cystine SCHEMBL1553822 0.81 GRIK1 (0.50) PTGS1SLC7A11ARG1ARG2NOS2
Cystine SCHEMBL27397844 0.81 GRIK1 (0.50) PTGS1SLC7A11ARG1ARG2NOS2
Cystine SCHEMBL457216 0.81 PTGS1 (0.73) PTGS1SLC7A11ARG1ARG2NOS2
Cystine SCHEMBL457217 0.81 PTGS1 (0.73) PTGS1SLC7A11ARG1ARG2NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1092264-C Chemically accelerated protein heat treatment COMMW SCIENT IND RES ORG (AU) 2002-10-09 CN disclosed
CN-1161067-A Chemically accelerated protein heat treatment COMMW SCIENT IND RES ORG (AU) 1997-10-01 CN disclosed