Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259179 | 0.87 | — | — | |
| SCHEMBL2891878 | 0.86 | — | — | |
| Methane SCHEMBL27513311 | 0.84 | MAOA (0.50) | MAOAMAOBLMNAALOX15BLM | |
| Hydrochloric Acid SCHEMBL9654361 | 0.84 | MAOA (0.50) | MAOAMAOBLMNAALOX15BLM | |
| SCHEMBL5662445 | 0.82 | MAOA (0.44) | MAOAMAOBLMNAACHEKDM4E | |
| SCHEMBL164711 | 0.82 | — | — | |
| Methane SCHEMBL27587764 | 0.81 | MAOA (0.48) | MAOAMAOBLMNAALOX15BLM | |
| SCHEMBL5930720 | 0.81 | — | — | |
| SCHEMBL3195621 | 0.81 | — | — | |
| Acetic Acid SCHEMBL16792627 | 0.80 | FFAR3 (0.39) | MAOAMAOBFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1770169-B1 | Process for producing glycine | ASAHI CHEMICAL IND (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-1243657-B1 | PROCESS FOR PRODUCING GLYCINE | ASAHI CHEMICAL IND (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1770169-A1 | Process for producing glycine | Asahi Kasei Kabushiki Kaisha (JP) | 2007-04-04 | — | — | EP | disclosed |
| US-6916638-B2 | Process for producing glycine | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20030040085-A1 | Process for producing glycine | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-02-27 | — | — | US | disclosed |
| EP-1243657-A1 | PROCESS FOR PRODUCING GLYCINE | Asahi Kasei Kabushiki Kaisha (JP) | 2002-09-25 | — | — | EP | disclosed |