Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940741 | 1.00 | TRPV1 (0.57) | TRPV1MEN1KMT2ATRPM8EGLN1 | |
| SCHEMBL3938804 | 0.92 | NPC1 (0.51) | TRPV1MEN1KMT2ATRPM8HDAC6 | |
| SCHEMBL3938813 | 0.92 | NPC1 (0.51) | TRPV1MEN1KMT2ATRPM8HDAC6 | |
| SCHEMBL13675624 | 0.83 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL13863924 | 0.82 | MEN1 (0.73) | TRPV1MEN1KMT2ATRPM8EGLN1 | |
| SCHEMBL3942178 | 0.80 | TRPV1 (0.54) | TRPV1MAPTNPC1POLBRAB9A | |
| SCHEMBL3942175 | 0.80 | TRPV1 (0.54) | TRPV1MAPTNPC1POLBRAB9A | |
| SCHEMBL4026823 | 0.78 | MEN1 (0.54) | TRPV1MEN1KMT2AHDAC6MAPT | |
| SCHEMBL4026831 | 0.78 | MEN1 (0.54) | TRPV1MEN1KMT2AHDAC6MAPT | |
| SCHEMBL3939567 | 0.78 | NPC1 (0.62) | TRPV1MEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | TRPV1 2741/4885MEN1 291/4885KMT2A 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.