Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | IAPP | P10997 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940917 | 1.00 | APP (0.60) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL11834908 | 1.00 | APP (0.60) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL11829489 | 0.96 | APP (0.61) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL11829482 | 0.96 | APP (0.61) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL7771761 | 0.94 | APP (0.62) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL19359034 | 0.94 | APP (0.62) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL19359036 | 0.94 | APP (0.62) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL11823517 | 0.91 | APP (0.58) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL11823522 | 0.91 | APP (0.58) | APPALOX5ATMMAPTLMNA | |
| SCHEMBL27629415 | 0.87 | ALOX5 (0.56) | APPALOX5ATMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133357-B1 | POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS | DU PONT (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7238841-B2 | Polymer-supported phosphorus ligands for catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-03 | — | — | US | disclosed |
| US-7098261-B2 | Polymer-supported phosphorus ligands for catalysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-08-29 | — | — | US | disclosed |
| EP-1604738-A2 | Process for the preparation of coumarin | E.I. du Pont de Nemours and Company (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1593431-A2 | Polymer-supported phosphorus ligands for catalysis | E. I. du Pont de Nemours and Company (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1593432-A2 | Polymer-supported phosphorus ligands for catalysis | E.I. du Pont de Nemours and Company (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1593430-A2 | Polymer-Supported phosphorus ligands for catalysts | E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20030228629-A1 | Polymer-supported phosphorus ligands for catalysts | FAGAN PAUL J (US) | 2003-12-11 | — | — | US | disclosed |
| US-6630604-B1 | Phosphine and phosphine oxide ligands are prepared using polymeric supports. These compounds can be easily cleaved from the support, and along with the corresponding supported compounds, used as ligands in the preparation of novel, | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-10-07 | — | — | US | disclosed |
| US-20030104476-A1 | Polymer-supported phosphorus ligands for catalysis | FAGAN PAUL J (US) | 2003-06-05 | — | — | US | disclosed |
| EP-1133357-A2 | POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000021663-A2 | POLYMER-SUPPORTED PHOSPHORUS LIGANDS FOR CATALYSIS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-20 | — | — | WO | disclosed |
| US-3998851-A | PREPARATION OF COUMARINS | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228629-A1 | Polymer-supported phosphorus ligands for catalysts | PHOSPHO1, PSPH, PNKP | APP 1753/4885ALOX5 2684/4885ATM 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.