Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780997 | 0.89 | CHRNA7 (0.47) | CHRNA7KCNH2 | |
| SCHEMBL780811 | 0.85 | CHRNA7 (0.69) | CHRNA7KCNH2 | |
| SCHEMBL14346886 | 0.85 | CHRNA7 (0.69) | CHRNA7KCNH2 | |
| SCHEMBL15841980 | 0.84 | CHRNA7 (0.58) | CHRNA7KCNH2 | |
| SCHEMBL3939516 | 0.81 | CHRNA7 (0.59) | CHRNA7KCNH2 | |
| SCHEMBL3929838 | 0.80 | CHRNA7 (0.67) | CHRNA7KCNH2 | |
| SCHEMBL779491 | 0.74 | CHRNA7 (0.46) | CHRNA7KCNH2 | |
| SCHEMBL3934162 | 0.74 | CHRNA7 (0.46) | CHRNA7 | |
| SCHEMBL3930902 | 0.74 | NPSR1 (0.48) | CHRNA7 | |
| SCHEMBL780210 | 0.74 | CHRNA7 (0.54) | CHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044038-B1 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CORNERSTONE THERAPEUTICS INC (US) | 2014-07-02 | — | — | EP | disclosed |
| EP-2044038-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | Cornerstone Therapeutics Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146066-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CRITICAL THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |