Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942940 | 1.00 | MAPT (0.47) | MAPTALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL3941054 | 0.95 | MAPT (0.49) | MAPTALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL3941048 | 0.95 | MAPT (0.49) | MAPTALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL3940683 | 0.93 | MAPT (0.50) | MAPTALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL4206065 | 0.91 | ALDH1A1 (0.51) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4206059 | 0.91 | ALDH1A1 (0.51) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4033045 | 0.89 | ALDH1A1 (0.49) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4202348 | 0.89 | MAPT (0.52) | MAPTALDH1A1L3MBTL1TP53POLB | |
| SCHEMBL3950752 | 0.87 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3941764 | 0.86 | MAPT (0.52) | MAPTALDH1A1L3MBTL1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |