SCHEMBL394298

SCHEMBL394298

Nc1ccc(C(=O)Nc2ccc(N)c(S(=O)(=O)O)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
POLB P06746 2/20 0.60
LMNA P02545 2/20 0.60
PKM P14618 1/20 0.60
APEX1 P27695 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CTDSP1 Q9GZU7 2/20 0.57
CASP6 P55212 1/20 0.57
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA12 O43570 1/20 0.56
CA9 Q16790 1/20 0.56
PRMT1 Q99873 3/20 0.51
ENPP2 Q13822 3/20 0.51
PTGS1 P23219 2/20 0.50
SETD7 Q8WTS6 1/20 0.49
MAPT P10636 3/20 0.48
SNCA P37840 1/20 0.48
HDAC3 O15379 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8952302 0.91 POLB (0.60) MEN1KMT2APOLBLMNAPKM
SCHEMBL17491043 0.89 KMT2A (0.51) MEN1KMT2APOLBLMNAPKM
SCHEMBL4905389 0.88 MEN1 (0.60) MEN1KMT2APOLBLMNAPKM
SCHEMBL8673667 0.88 KCNK3 (0.54) MEN1KMT2APKMCA1CA2
SCHEMBL10877294 0.87 MEN1 (0.58) MEN1KMT2APOLBLMNAPKM
SCHEMBL11736141 0.85 MEN1 (0.61) MEN1KMT2APOLBLMNATDP1
SCHEMBL4905086 0.85 PTGS1 (0.54) MEN1KMT2APRMT1ENPP2PTGS1
SCHEMBL11169136 0.85 ENPP2 (0.58) MEN1KMT2APOLBLMNAPKM
SCHEMBL11702580 0.83 MEN1 (0.64) MEN1KMT2APOLBLMNAPKM
SCHEMBL29402666 0.83 POLB (0.58) MEN1KMT2APOLBLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4211457-A None JP disclosed
JP-61051064-A None JP disclosed
US-8101731-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION 2012-01-24 US disclosed
US-8101731-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION 2012-01-24 US disclosed
US-8101731-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION 2012-01-24 US disclosed
US-20100199443-A1 YELLO ANIONIC DISAZO DYES LENNARTZ MICHAEL 2010-08-12 US disclosed
US-20100199443-A1 YELLO ANIONIC DISAZO DYES LENNARTZ MICHAEL 2010-08-12 US disclosed
US-20100199443-A1 YELLO ANIONIC DISAZO DYES LENNARTZ MICHAEL 2010-08-12 US disclosed
US-7723494-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723494-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0449250-A1 Trisazo compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-02 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed
US-4875903-A PRINTING,DYEING SANDOZ LTD. (CH) 1989-10-24 US disclosed
JP-S6151064-A TRISAZO COMPOUND AND METHOD FOR DYEING PAPER PULP BY USING SAME NIPPON KAYAKU CO LTD 1986-03-13 JP disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0001629-B1 WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-08-12 EP disclosed
EP-0001629-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 EP disclosed