Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 12/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.57 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951463 | 0.86 | SLC6A4 (0.61) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL3943608 | 0.86 | SLC6A4 (0.52) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL4014475 | 0.85 | SLC6A4 (0.60) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL4017870 | 0.85 | SLC6A4 (0.53) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL4016150 | 0.84 | SLC6A4 (0.78) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL3947165 | 0.83 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL3941094 | 0.80 | SLC6A4 (0.67) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL27014965 | 0.80 | SIGMAR1 (0.66) | HRH3KCNH2 | |
| SCHEMBL3949020 | 0.79 | SLC6A4 (1.00) | SLC6A4HRH3SLC6A2SLC6A3HTR2A | |
| SCHEMBL3950804 | 0.78 | SLC6A4 (0.63) | SLC6A4HRH3SLC6A2SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049473-A2 | SUBSTITUTED BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008002820-A2 | SUBSTITUTED BENZYL AMINE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-03 | — | — | WO | claimed |