Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952013 | 0.97 | PKM (0.56) | PKMRXFP1TP53 | |
| SCHEMBL3943430 | 0.94 | PKM (0.58) | PKMRXFP1TP53 | |
| SCHEMBL3946602 | 0.94 | PKM (0.61) | PKMRXFP1TP53 | |
| SCHEMBL3941330 | 0.93 | PKM (0.54) | PKMRXFP1 | |
| SCHEMBL3946997 | 0.92 | PKM (0.50) | PKMRXFP1TP53 | |
| SCHEMBL3943805 | 0.92 | PKM (0.60) | PKMRXFP1 | |
| SCHEMBL3942773 | 0.90 | RXFP1 (0.54) | PKMRXFP1 | |
| SCHEMBL13942592 | 0.90 | TP53 (0.45) | PKMTP53 | |
| SCHEMBL3940586 | 0.90 | PKM (0.68) | PKMRXFP1 | |
| SCHEMBL3941131 | 0.90 | MEN1 (0.52) | PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |