Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.74 |
| ▸ | PPARG | P37231 | 8/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13821920 | 1.00 | EPHX2 (0.74) | EPHX2PPARGLDHAPPARAGLA | |
| SCHEMBL28201178 | 0.89 | EPHX2 (0.64) | EPHX2PPARGLDHAPPARAGLA | |
| SCHEMBL9514160 | 0.88 | EPHX2 (0.60) | EPHX2PPARGLDHAPPARAKMT2A | |
| SCHEMBL31483374 | 0.86 | EPHX2 (0.58) | EPHX2PPARGLDHAPPARAGLA | |
| SCHEMBL4453569 | 0.83 | PPARG (0.72) | EPHX2PPARGLDHAPPARAKMT2A | |
| SCHEMBL12191490 | 0.83 | PPARG (0.72) | EPHX2PPARGLDHAPPARAKMT2A | |
| SCHEMBL490486 | 0.83 | LDHA (0.69) | EPHX2PPARGLDHAPPARAGLA | |
| SCHEMBL27707711 | 0.83 | EPHX2 (0.55) | EPHX2PPARGLDHAPPARAPPARD | |
| SCHEMBL22240364 | 0.82 | EPHX2 (0.73) | EPHX2PPARGPPARAKMT2A | |
| SCHEMBL11762033 | 0.82 | LDHA (0.57) | EPHX2PPARGLDHAPPARAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | disclosed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | PPARA, PPARG, PPARD | EPHX2 1279/4885PPARG 2/4885LDHA 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.