Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.64 |
| ▸ | PPARD | Q03181 | 13/20 | 0.64 |
| ▸ | PPARG | P37231 | 12/20 | 0.64 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.60 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.60 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.60 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.60 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.60 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945778 | 0.84 | PPARA (0.64) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL3944237 | 0.84 | PPARA (0.63) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL3943372 | 0.78 | PPARD (1.00) | PPARAPPARDPPARG | |
| SCHEMBL3948697 | 0.76 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6494547 | 0.76 | PPARA (0.74) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL4041201 | 0.76 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL3946807 | 0.76 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL28021287 | 0.75 | PPARA (0.75) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL10077534 | 0.75 | PPARA (0.75) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6374864 | 0.75 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | claimed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | claimed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | claimed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | claimed |
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | disclosed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | PPARA, PPARG, PPARD | PPARA 1/4885PPARD 3/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.