Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945413 | 0.95 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL4521555 | 0.94 | RXFP1 (0.59) | RXFP1MEN1KMT2ATSHRHTT | |
| SCHEMBL3945499 | 0.94 | TSHR (0.49) | RXFP1MEN1KMT2ATSHRHTT | |
| SCHEMBL3952068 | 0.93 | MEN1 (0.48) | RXFP1MEN1KMT2A | |
| SCHEMBL3942708 | 0.93 | RXFP1 (0.55) | RXFP1MEN1KMT2ATSHRHTT | |
| SCHEMBL13943102 | 0.93 | RXFP1 (0.49) | RXFP1MEN1KMT2ATSHRHTT | |
| SCHEMBL3951120 | 0.93 | TSHR (0.47) | TSHRHTTMAPK10 | |
| SCHEMBL3943436 | 0.90 | TSHR (0.46) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL3952481 | 0.90 | PKM (0.54) | RXFP1TSHRHTTMAPK10 | |
| SCHEMBL13942370 | 0.90 | TSHR (0.46) | RXFP1MEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |