⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528291 | 1.00 | — | — | |
| SCHEMBL7525583 | 1.00 | — | — | |
| SCHEMBL7521276 | 1.00 | — | — | |
| SCHEMBL7517021 | 1.00 | — | — | |
| SCHEMBL1343935 | 0.76 | — | — | |
| SCHEMBL7524037 | 0.73 | — | — | |
| SCHEMBL7515259 | 0.73 | — | — | |
| SCHEMBL7512780 | 0.73 | — | — | |
| SCHEMBL7518750 | 0.73 | — | — | |
| SCHEMBL7514639 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221014560-U | Device for collecting tail gas condensate in (S) 4-chloro-3-hydroxybutyronitrile production | 山东宏旭化学股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| EP-0347818-A2 | Process for preparing 3-pyrrolidinol | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | claimed |
| CN-216594328-U | Sampling device for closed reaction kettle | 山东宏旭化学股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110372525-A | One kind synthesizing the preparation method of l-carnitine using R- (-)-epoxychloropropane as starting material | 抚顺顺能化工有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-109628511-A | The environmentally protective preparation method of one kind (R)-(-) -4- cyano-3-hydroxy ethyl butyrate | 抚顺顺能化工有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-104745556-B | One kind restructuring halide alcohol dehalogenase, mutant, engineering bacteria and its application | 浙江工业大学 | 2017-09-22 | — | — | CN | disclosed |
| CN-105968086-A | Method for synthesizing ADA | 南京杰运医药科技有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-103649068-B | A kind of statins drug midbody and its preparation method | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-06-01 | — | — | CN | disclosed |
| US-8580555-B2 | Recombinant halohydrin dehalogenase polypeptides | CODEXIS, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8535910-B2 | Halohydrin dehalogenases and related polynucleotides | CODEXIS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-20120220002-A1 | Recombinant Halohydrin Dehalogenase Polypeptides | CODEXIS, INC. (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2006091470-A2 | IMPROVED HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES | CODEXIS, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| US-20060099700-A1 | Enzymatic polypeptide comprising halogenase activity for use in production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters; bioremediation; pollution control | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2006-05-11 | — | — | US | disclosed |
| EP-1654356-A1 | IMPROVED HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES | Codexis, Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20050272064-A1 | Halohydrin dehalogenases and related polynucleotides | CODEXIS, INC. | 2005-12-08 | — | — | US | disclosed |
| US-20050153417-A1 | Halohydrin dehalogenases and related polynucleotides | CODEXIS, INC. | 2005-07-14 | — | — | US | disclosed |
| WO-2005017141-A1 | IMPROVED HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES | CODEXIS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| EP-0347818-A2 | Process for preparing 3-pyrrolidinol | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-12-27 | — | — | EP | disclosed |