Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951093 | 0.92 | HTT (0.55) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3945166 | 0.90 | HTT (0.57) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3951486 | 0.90 | HTT (0.53) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3947317 | 0.90 | HTT (0.56) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3943301 | 0.90 | HTT (0.47) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL13942062 | 0.89 | HTT (0.51) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3949251 | 0.89 | HTT (0.55) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL13942349 | 0.89 | HTT (0.54) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3942911 | 0.88 | HTT (0.63) | HTTSMN1; SMN2ALDH1A1TSHRPKM | |
| SCHEMBL3948692 | 0.88 | HTT (0.63) | HTTSMN1; SMN2ALDH1A1TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |