Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27941248 | 0.84 | TSHR (0.42) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL9728466 | 0.79 | TSHR (0.41) | TSHRALDH1A1HTR6CA1CA2 | |
| SCHEMBL28333967 | 0.79 | TSHR (0.41) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL11037152 | 0.79 | TSHR (0.49) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL8827511 | 0.79 | TSHR (0.52) | TSHRALDH1A1NT5ELMNAMPO | |
| Methane SCHEMBL11511469 | 0.77 | TSHR (0.50) | TSHRALDH1A1NT5ELMNAMPO | |
| Fluoride Ion SCHEMBL28590196 | 0.77 | TSHR (0.39) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL27588753 | 0.76 | CA1 (0.43) | TSHRALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL31386568 | 0.76 | TSHR (0.52) | TSHRALDH1A1NT5ELMNAMPO | |
| SCHEMBL7607789 | 0.76 | TSHR (0.52) | TSHRALDH1A1NT5ELMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883383-B2 | Charge transport layer comprising fluoroacyl arylamine | XEROX CORPORATION (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140141365-A1 | Charge Transport Layer Comprising Fluoroacyl Arylamine | XEROX CORPORATION (US) | 2014-05-22 | — | — | US | disclosed |
| US-8481240-B2 | Electrophotographic imaging member and method of making same | XEROX CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| CN-101271285-B | Photoreceptor device having a self-assembled patterned binder layer | XEROX CORP | 2012-11-07 | — | — | CN | disclosed |
| US-20120063818-A1 | Electrophotographic Imaging Member and Method of Making Same | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2012-03-15 | — | — | US | disclosed |
| US-8101327-B2 | Charge transport and overcoating layers formed by combining a film forming polycarbonate binder and a hole transporting hydroxy triarylamine compound; surface energy-reducing silicone is crosslinked with heat or ultraviolet radiation and the coating is dried to remove solvent | XEROX CORPORATION (US) | 2012-01-24 | — | — | US | disclosed |
| US-20080280220-A1 | Electrophotographic imaging member and method of making same | XEROX CORPORATION. | 2008-11-13 | — | — | US | disclosed |
| CN-101271285-A | Photoreceptor device having a self-assembled patterned binder layer | XEROX CORP (US) | 2008-09-24 | — | — | CN | disclosed |
| US-20080057424-A1 | Overcoat for electrophotographic imaging member and methods of making and using same | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |
| US-5846681-A | Multilayer imaging member having improved substrate | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |
| US-5830613-A | Electrophotographic imaging member having laminated layers | XEROX CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |