Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289293 | 0.91 | TSHR (0.42) | TSHRDHFRSMN1; SMN2TDP1F2 | |
| SCHEMBL8378769 | 0.85 | ALDH1A1 (0.50) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL28278748 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2TDP1ALDH1A1GAANPC1 | |
| SCHEMBL11244972 | 0.81 | F2 (0.50) | TSHRTDP1F2PRSS1PRSS2 | |
| SCHEMBL7607789 | 0.80 | TSHR (0.52) | TSHRDHFRSMN1; SMN2TDP1F2 | |
| SCHEMBL31386568 | 0.80 | TSHR (0.52) | TSHRDHFRSMN1; SMN2TDP1F2 | |
| SCHEMBL394372 | 0.79 | TSHR (0.44) | TSHRDHFRSMN1; SMN2TDP1F2 | |
| Potassium SCHEMBL30488660 | 0.79 | TSHR (0.50) | TSHRDHFRSMN1; SMN2TDP1F2 | |
| SCHEMBL28603284 | 0.79 | TSHR (0.50) | TSHRDHFRSMN1; SMN2TDP1F2 | |
| SCHEMBL27484632 | 0.79 | TSHR (0.50) | TSHRDHFRSMN1; SMN2TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1745056-A | Acetoacetylation of alcohols, thiols, and amines in microreactors | CLARIANT GMBH (DE) | 2006-03-08 | — | — | CN | disclosed |
| US-4540776-A | Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4354968-A | Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-19 | — | — | US | disclosed |
| US-4348204-A | COTTON, REGENERATED CELLULOSE, PAPER; TETRAKISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4143033-A | WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |