SCHEMBL394397

SCHEMBL394397

O=C1OC(=O)C2C3CCC(CC3)C12

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.55
GMNN O75496 1/20 0.55
PPM1B O75688 1/20 0.55
LMNA P02545 1/20 0.55
PPP1CC P36873 1/20 0.55
TFPI2 P48307 1/20 0.55
RAB9A P51151 1/20 0.55
PPP5C P53041 1/20 0.55
PPP1CA P62136 1/20 0.55
PMP22 Q01453 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
TP53 P04637 1/20 0.55
CYP2D6 P10635 1/20 0.55
NFKB1 P19838 1/20 0.55
THPO P40225 1/20 0.55
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17243591 1.00 KDM4E (0.55) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL3196649 0.92 KDM4E (0.48) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL3196644 0.92 KDM4E (0.48) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL12268148 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL10050520 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL9605761 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL10194829 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL9820453 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL19215231 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL17988728 0.88 LMNA (0.50) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838453-B Polymer heteronuclear porphyrin complex and preparation method and application thereof 中国科学院长春应用化学研究所 2024-05-24 CN claimed
CN-115838453-A High-molecular heteronuclear porphyrin complex and preparation method and application thereof 中国科学院长春应用化学研究所 2023-03-24 CN claimed
EP-2307476-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2011-04-13 EP claimed
WO-2009152068-A1 ASYMMETRIC CYCLIC DIESTER COMPOUNDS FERRO CORPORATION (US) 2009-12-17 WO claimed
US-20090312470-A1 Asymmetric Cyclic Diester Compounds FERRO CORPORATION (US) 2009-12-17 US claimed
EP-0362804-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-01-03 EP claimed
EP-0361514-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1995-11-29 EP claimed
US-4954407-A Modified methacrylate polymer FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US claimed
EP-0362804-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP claimed
JP-4202419-A None JP disclosed
JP-2038415-A None JP disclosed
JP-3277622-A None JP disclosed
US-12441841-B2 Optically transparent polyimides AKRON POLYMER SYSTEMS, INC. (US) 2025-10-14 US disclosed
US-20250129221-A1 CADAVERINE-BASED POLYIMIDES AKRON POLYMER SYSTEMS, INC. (US) 2025-04-24 US disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
US-4745117-A NEUROLEPTIC AGENTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1988-05-17 US disclosed
EP-0261688-A1 Imide derivatives, and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1988-03-30 EP disclosed
EP-0196096-A2 Imide derivatives, their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1986-10-01 EP disclosed
US-4543355-A Substituted succinimides, compositions and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-24 US disclosed
US-4507303-A Succinimide derivatives, compositions and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312470-A1 Asymmetric Cyclic Diester Compounds DDT, PCNA, AADAC KDM4E 1680/4885GMNN 1447/4885PPM1B 3183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.